Nexgard vs Seresto

Nexgard Vs Seresto

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When considering flea and tick control options for your furry companions, the choice between Nexgard and Seresto can present a dilemma. Each product offers distinct features in terms of administration, active ingredients, and duration of protection. Understanding the nuances of these two popular treatments is crucial in making an informed decision that aligns with your pet’s needs and your preferences as a pet owner. As we delve into the specifics of Nexgard vs Seresto, a clearer picture emerges, shedding light on which option may be the optimal choice for safeguarding your pet against pesky parasites.

Key Takeaways

  • Nexgard is an oral treat, while Seresto is a collar for pets.
  • Nexgard kills 100% of fleas and ticks within 24 hours with Afoxoflaner.
  • Seresto repels ticks within 6 hours and starts killing fleas in 24 hours.
  • Nexgard is not available for cats, but Seresto offers collars for feline use.
  • Nexgard requires a prescription, while Seresto is available over the counter.

Application Methods

When comparing Nexgard and Seresto in terms of application methods, Nexgard is administered orally as a treat for pets, while Seresto is designed as a collar for comfortable wear around the pet’s neck.

Nexgard offers a convenient solution for pet owners who prefer administering treatments through oral means. The chewable tablet form of Nexgard makes it easier to ensure that pets consume the full dosage.

On the other hand, Seresto provides a hassle-free option by simply placing the collar around the pet’s neck, eliminating the need for monthly applications. This collar design allows for continuous protection against fleas and ticks, offering a practical and long-lasting solution for pet owners seeking ease of application.

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Active Ingredients

A key differentiating factor between Nexgard and Seresto is the active ingredients utilized in their formulations.

Nexgard contains Afoxoflaner, which is effective in killing 100% of fleas and ticks within 24 hours. It is also the only FDA-approved product for Lyme disease prevention.

On the other hand, Seresto utilizes Flumethrin and Imidacloprid to combat fleas and ticks, starting to kill fleas within 24 hours and repelling ticks within six hours of application.

Both products have distinct active ingredients that cater to different aspects of flea and tick control. Pet owners should consider these differences when choosing between Nexgard and Seresto for their pets’ parasite protection needs.

Availability for Cats

For feline owners seeking parasite protection options, it is important to note that Nexgard is not available for cats, whereas Seresto offers collars specifically designed to repel fleas and ticks in cats.

While Nexgard is a popular oral treatment loved by many pets, it is not formulated for feline use. On the other hand, Seresto provides a convenient collar application method that is comfortable for cats to wear.

This difference in availability means that cat owners looking for a flea and tick prevention solution may find Seresto to be a suitable option tailored to their feline companions’ needs. Therefore, when considering parasite protection for cats, Seresto stands out as a viable choice due to its availability and effectiveness.

Purchase and Prescription

Requiring a prescription from a veterinary professional, Nexgard distinguishes itself from Seresto in terms of purchase and usage requirements.

While Seresto is available over the counter, Nexgard necessitates a prescription, ensuring that pet owners consult with a veterinarian before starting the treatment.

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This prescription requirement allows vets to provide guidance on potential side effects, precautions, and the most suitable dosage for the pet.

By obtaining Nexgard through a prescription, pet owners can rest assured that they are using the product correctly and safely.

This extra step adds a layer of assurance and expertise to the purchasing process, demonstrating Nexgard’s commitment to responsible pet care through professional oversight.

Cost and Usage Considerations

Moving forward from the discussion on Nexgard’s prescription requirement, an important aspect to consider is the cost and usage considerations associated with both Nexgard and Seresto pet treatments.

Seresto is applied once every 8 months, offering convenience for pet owners compared to Nexgard, which requires a monthly tablet.

Some pet owners may opt to switch between treatments based on their specific preferences or their pets’ conditions. Seresto may be preferred for dogs with certain health conditions.

Understanding these differences in cost, frequency of application, and individual pet needs is crucial for pet owners to make an informed decision on which treatment option is most suitable for their furry companions.

Frequently Asked Questions

Are There Any Known Drug Interactions With Nexgard or Seresto?

Regarding Nexgard and Seresto, it is crucial to inquire about potential drug interactions with other medications or supplements your pet is taking. Consult a veterinarian to ensure the safety and efficacy of these products.

Can Nexgard or Seresto Be Used Alongside Other Flea/Tick Preventatives?

Yes, it is generally not recommended to use Nexgard or Seresto alongside other flea/tick preventatives unless advised by a veterinarian. Combining different products without professional guidance can lead to overdosing, adverse reactions, or decreased effectiveness.

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How Long Does It Take for Nexgard or Seresto to Be Fully Effective?

The time for Nexgard or Seresto to be fully effective varies. Nexgard kills 100% fleas and ticks within 24 hours, while Seresto starts killing fleas in 24 hours and repels ticks within six hours. Consult a vet for specific guidance.

Are There Any Natural Alternatives to Nexgard and Seresto?

When exploring natural alternatives to traditional flea and tick preventatives like Nexgard and Seresto, options such as essential oils, diatomaceous earth, and herbal collars can be considered. Consult with a veterinarian for guidance on effective and safe alternatives.

Can Nexgard or Seresto Be Used on Pets With Sensitive Skin?

Pets with sensitive skin should consult a veterinarian before using Nexgard or Seresto. Both products have specific application methods and active ingredients that may affect sensitive skin differently. Professional guidance ensures safe and effective treatment for pets.


In conclusion, Nexgard and Seresto are both effective options for flea and tick control in pets, offering different application methods and active ingredients.

Nexgard, administered orally, contains Afoxoflaner for rapid parasite elimination, while Seresto utilizes Flumethrin and Imidacloprid in a collar form for long-lasting protection.

Both products cater to varied preferences and pet needs, providing pet owners with options for keeping their furry friends safe from parasites.

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